Here's a Desert Bus playthrough. The player collects 3 points by completing the trip three times, a feat which normally takes 8 hours each way, but the video is at 3x speed, so you see it in "only" 8 hours. Catch the excitement at 2:45:20 as the player scores their first point!

https://www.youtube.com/watch?v=2LtiHla1dNg

That article credits Teller only, in the title, and primarily, in the body. And Desert Bus was a parody, not a game per se.

I would like to see an update of Desert Bus that uses all the latest 3D technology and satellite data like they put in flight simulators.

I mean, Teller referred to it as "a game that just reflects reality", so how real could you make it?

Recreate a real bus, but the most boring one possible.

...Desert Bus 2020

You could probably make a mod for American Truck Simulator VR.

A parody game is still a game.