Mutiny works with any CMS so shopify is technically fine. What type of personalization do you want to do? If you have a ton of products and want to dynamically change the product you show, it might be better to build a server side implementation. We are not quite optimized for big e-commerce sites who want to optimize SKUs - that's much more of a b2c use case. Send me the site and what you are trying to do, and I can take a look.