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Re:Ask HN : Which opensource project for beginner python dev... by patd on Friday January 21, 2011 @11:59AM (#2127914)
Find a project that you already use or that you like that supports plugins. Write one plugin and learn by looking at other plugins.

On the top of my head: deluge (bittorrent client) emesene (MSN client) XBMC (media center)

If you're a Gnome user, most applications support Python plugin (Nautilus, GEdit, ...)

Shameless plug on my part, you could make a plugin for my open source project called periscope. It downloads video subtitles from various websites http://code.google.com/p/periscope/

Re:Ask HN : Which opensource project for beginner python dev... by simplyJump on Friday January 21, 2011 @01:28PM (#2128298)
This also is a pretty good idea. I know django supports plugins. I've written some for my site.