Apologies if I'm misreading your comment, but not necessarily. If something affects the production of your germ cells (sperm or eggs) or the cells themselves, then it can affect your children. Something as simple as a mutation in the sperm or egg leading to offspring will be carried by your children.

If, however, your exposure leads to mutations in a genetic region that affects sperm or eggs, your children may be perfectly fine except for their germ cells, which can lead to an issue in their children, your grandchildren.