I previously worked in an environment where iPads were distributed to staff; the team responsible for supporting them had toothpicks on hand for this exact reason.

An argument may exist for lint etc being harder to clean out of a USB-C port once it had made its way in there, but haven't witnessed it myself yet.

Anecdotes can be given all day, but I would suggest it's a potential problem for any port of similar size being placed in pockets and bags.