Well, art is iterative. It would be weird to create music with no ties to the past. It's hard to imagine what that would sound like because there would be no precedent!

The closest thing I can think of to that though is the album Strawberry Jam by Animal Collective. The song Bonefish is a good representative sample. My brain couldn't process it at first... It made no sense until after a few listens and a hit of weed.