Re:Inbreeding in a European ancestry sample from the contemp...
by blueblimp on Sunday October 06, 2019 @06:35PM
(#21175677)
For traits, the effect on non-double first cousins can be linearly approximated, which (as far as I know) is a good approximation for inbreeding depression.
For example, taking Fluid Intelligence Score (basically how smart you are), in Table 3, its extrapolated effect size is -3.43, so:
First cousin (relationship coefficient 0.125, inbreeding coefficient 0.0625) would give -0.214 to FIS. To put that in context, for medication, that would be considered a small effect size. So inbreeding at that level is a bit like taking a stupid pill.
For example, taking Fluid Intelligence Score (basically how smart you are), in Table 3, its extrapolated effect size is -3.43, so:
First cousin (relationship coefficient 0.125, inbreeding coefficient 0.0625) would give -0.214 to FIS. To put that in context, for medication, that would be considered a small effect size. So inbreeding at that level is a bit like taking a stupid pill.