Depends on what kind of drone. Flying a FPV / racing drone requires some skill (but not much if you've played games). Flying acrobatic drones in third person (eg. https://www.youtube.com/watch?v=duHCDwH9G2M) requires a lot of skill.

Compared to those, flying drones like those from DJI require almost no skill. These drones do some form of obstacle avoidance on their own. You basically have to tell them where to fly and they will go there. Some are smarter than others in how they execute the manoeuvres, but some common sense will get you a long way with those.