We're finally getting around to migrating away, and we've settled on Twitter's github.com/pantsbuild/pants which is like Google's Bazel except that it's jankier in every way _except_ that Pants supports Python while Bazel doesn't (Bazel advertises Python support, but it doesn't work as the many Python 3 issues in their issue tracker can attest). The nicest thing about Pants is that it builds pex files (github.com/pantsbuild/pex) which are executable zip files that ship all of your dependencies except the Python interpreter and shared objects.
I'm still not very satisfied with this solution, and it's still far, far worse than Go's dependency management and packaging model, but it's a dramatic improvement over Pipenv, virtualenv, etc (gives us both reproducibility and performance).
The point is that the static binary created by go is a single file that you copy into place and run. It is a lot simpler.
I had heard that the Python packaging and deployment story had got a lot better in recent years, but this sounds like it still falls far short of table stakes.