uBlock Origin can be configured to do much more than a simple list based filter (like EasyList, etc). [1] It's not quite the same as detecting, but it's incredibly configurable, and that functionality can't be used when list based filtering is all that's allowed.

And I'm aware PiHole is just DNS filtering, but an extra layer of blocking is useful.

1. https://github.com/gorhill/uBlock/wiki/Dynamic-filtering