As someone who grew up in rural Louisiana in the southeastern US, if you're being charged by a hog, you're better off with a .45 semi-automatic handgun such as a Colt 1911 / clone. That will likely be the difference between "I just had a mild heart attack" and "I'm in the ICU". As far as hunting, sure, a bolt-action rifle in the .30-caliber range, such as a .308 or .30-06 is fine, since you have distance on your side, particularly distance that isn't rapidly decreasing with some tusks headed your way with your name on them.