Where can you invest that would still recognize those funds as yours after 222 years?

You'd have to form some kind of trust, the "Swizec is in space for 200 years trust" to handle your investments for you with a constitution that lays out how long it is expected for you to be gone.

You might come back to discover that after several generations without oversight your trust has invested in bombing children and enriching the fund managers. I dunno.

You still get in trouble I think. Have any political regimes been stable enough in the past 222 yaers for the trust to survive?

All of Europe has gone through multiple revolutions, USA was only 30 years old back then so you wouldn’t have considered it ... that leaves what, the UK? Any parts of Asia that survived since 1797?

With travel time that long , you have to consider technological advancement at home. Just imagine that you look out of your window after travelling for 70 years and there is this other ship overtaking yours with ease.

Going down in history as "First to leave, last to arrive". Brutal

The colony of New South Wales was founded in 1788 and there is a fairly direct lineage of laws from there to modern-day Australia, and going backwards also a direct lineage of laws in Britain.

Nothing is risk-free, diversify! The likeliest outcome aside from coming back to nothing is you come back to an institution that is nothing like what it started.

It's been done actually. Ben Franklin established a trust that lasted over two hundred years by design.

https://www.nytimes.com/paidpost/franklin-templeton/investin...

I admit I have some bias here being British, and just assuming the banking system won’t go under. I think if I was actually going to execute on this I’d end up finding a bunch of countries with well-established trust law and spread it between them.