Yes. Here's a personal anecdote to illustrate. Years ago I had dental surgery, and the dentist prescribed a new and very expensive antibiotic for me. I was poor at the time, and paying for that was a serious hardship.
The next day I had a severe allergic reaction to it, and the dentist replaced that prescription with plain old penicillin (which cost me $10 for the complete treatment). I was absolutely furious that he didn't go with the affordable and time-tested treatment first.
New interventions often aren’t tested head to head against their alternatives. Or inadequately tested against them.
So we have no idea if they’re even better, but manufacturers don’t want to risk the embarrassment of evidence that they’re inferior.