Tories whine about Brussels forcing all of this stuff onto the UK, they'll gleefully strip it away at the first opportunity. It might turn out to be good for business after all, but in the same way the Iraq war was.
While it's true that the Tory party of old (charitably until ~2015) may have cared about competitiveness for business, that party is now dead - overtaken by the extreme right. The only thing that matters to them at this stage is power, and personal enrichment, and they have become masters of disinformation and confusion to ensure it -- a job made much easier by the generally awful state of the press in the UK. It's a shame that the opposition are, as you say, no better.
Not friendly for manufacturing (relying on JIT inventory management across borders and regulatory alignment for exports).
Not friendly for scientific spin-off/catapult startups, which rely on the the universities attracting researchers and research grants.
Not friendly for anything relying on a large number of domestic customers with disposable income (e.g. retail), because everyone will have to save up against the fear of sudden unemployment or US-style healthcare bills.
Basically, most things that are not good for the general public are also not good for most business, because in the end, businesses rely on customers buying their product (or in a B2B scenario, their clients' products and so on).
And the day after this article was written the UK government announces a review of HS2 - probably for rather short term political reasons:
https://www.bbc.co.uk/news/uk-politics-49420332