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Re:The GitHub registry public beta is live by alexbecker on Tuesday August 20, 2019 @07:17PM (#20753226)
Running a python package registry has some unique challenges, so it makes sense not to start with it (I run such a registry: https://pydist.com).

For example, Python has a distinction between distributions (the actual file downloaded, e.g. a tarfile or a manylinux1 wheel) and versions that doesn't exist in most other languages.

Re:The GitHub registry public beta is live by takeda on Tuesday August 20, 2019 @09:55PM (#20754000)
All of these concerns are handled on client side, in the end all python needs is an http server, it can be actually hosted on S3.