I'm not sure the people you cite were following a Disney formula. But along the lines you're drawing, sometimes they are persecuted (Galileo) sometimes die in poverty (Van Gogh) sometimes killed by a mob (Hypatia of Alexandria) and sometimes they are hounded to suicide (Allan Turing, Aaron Swartz)

But far more often, none of those things. And either way, I never have heard such people say they wish they'd been average.