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Re:Senescent cells stop producing nucleotides: new research by hundreddaysoff on Saturday July 27, 2019 @10:57AM (#20542288)
It's irreversible because it's at a greater rate than DNA repair. At least, it is in mammalian non-germ cells.

Also, there isn't just one kind of DNA damage or DNA repair. Different kinds of damage have different orders of badness of effects and have different priors of happening by our cellular machinery.

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