I think that not working in an industry often gives you a unique perspective that might as well make you more likely to spot a particular gap its regulars are taking for granted.

Of course you will need some insider knowledge, but oftentimes not all that much - a lot of industries develop similar approaches to solving similar or analogous problems, but with varying access to the underlying knowledge/skill needed to making it effective.

You will need to be a bit of an anthropologist and a good communicator to get the relevant information from people whose working days you plan to optimize/improve with software.

I'd say observation with an unspoiled eye can work wonders :).