> Nutrition is not a solved equation. We simply do not know how exactly various foods affect our health, the extent that human genetics and microbiome affect “proper” nutrition for a person, what all the essential nutrients are, what the immunoresponse to various foods are, and any number of unknown unknowns about diet. Any claims to the contrary are irresponsible at best.

Nevertheless the same applies to the way we changed our diets in relatively recent times, and yet that hasn't stopped us.