Assuming we're talking about drugs that are necessary for survival (or at least having a normal life) and are either government-granted monopolies or have very limited sources, then drug-sellers selling to individuals can engage in price gouging, which is clearly immoral to me (and most everybody else). If you aren't sure why, there's a big literature on price gouging that should help.

However, one can't price gouge on games. There are infinite games to play, many of them free and a great many more are inexpensive. If people don't get a particular game, they will not die or live a terrible life. So game sellers can price as they please and set reasonable terms without any big ethical issues.