It costs an arm and leg and takes a while to learn, but it makes every other keyboard I've touched feel downright archaic!
If you have a modifier-heavy workload the keyboard gets lost. A few times a day I have to flip through all the modifiers to get one unstuck. Probably once a week I have to power cycle it since that isn't sufficient. there is so much room in the case I also wonder why they haven't invested a little effort and made a bluetooth with battery option - I've been sorely tempted to do this but never could justify the time.
The thing I really like* about this keyboard aside from modifiers on thumbs is that you can effectively use it on your lap and shift positions. it feels a little more like a musical instrument that way.
Something I've been thinking about getting is a clip on 12 inch monitor + RasPi, it would be such a great remote development setup for cafes.