I have to agree here, having worked with Filemaker previously. However, it really does shine for small business type applications where you need to set something up in a hurry, have only a handful of people using it and they're not very technical. Once that business grows though (eg. they need SQL/Web access) then you're better off migrating to something else.

<plug>My startup http://www.formlis.com (a hybrid wiki and database) is trying to compete in this area</plug>

Yep, that's basically my experience, too.

However, that seems to be EVERYONE's experience, which makes me think that it's a good spot to become an expert in, since nobody else wants to go through and learn it.