A lot of what I’ll call “third tier” cities (Cleveland, Boise, Reno, etc.) are facing housing shortages precisely because a lot of people were priced out of larger cities. So housing shortages are popping up in those places as well, driving up home prices dramatically. I know at least one of those cities where the average price of a 2br house jumped from $300k to $600k in 5 years.
As usual, the problems are NIMBYs and restrictive zoning with a heavy preference for single-family homes. But moving to smaller, cheaper cities is only a short-term solution. The long-term solution is to build more, denser housing.
Reno's listing price $231/ft^2 up from $151/ft^2 five years ago, but keep in mind that Reno was rather badly hit by 2008: median sales prices for 2br homes peaked at about $284,000 in 2006, bottomed at about $75,000 in 2011, and are currently back up to $271,000 (https://www.trulia.com/real_estate/Reno-Nevada/market-trends...).
It’s a problem that will get worse before it gets better, and the cities that can figure out how to provide housing that someone working minimum wage can afford will be the winners.