The Inter Planetary File System has the potential to radically change content hosting to become truly decentralized. This report names some of the most pressing barriers to widespread adoption of ipfs.

In my opinion the biggest issue is terrible documentation on ipfs.io (as noted by the report). The "Getting Started" page fails to explain the basic structure of ipfs and uses jargon that isn't defined. This lack of documentation prevents even tech savvy users from adopting ipfs.