Total cholesterol and all-cause mortality – a study among 13M adults

Re:Total cholesterol and all-cause mortality – a study among... by virtuallynathan on Sunday June 09, 2019 @11:45AM (#20139906)

My comment is more general, not specifically in response to the specifics of the article on TC. FWIW, TC is probably not a great measure on an individual basis, but sort of interesting population-wide.

Yes, folks agree high HDL is good, high LDL is bad. However, drug trials to raise HDL didn't work so well.

> "Are there really any studies that attribute atherosclerosis to bacteria, or some of the other conditions you describe?"

Yes! Many!

- "Accelerated Atherosclerosis in Autoimmune Rheumatic Diseases" https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA....

- "Deposition and hydrolysis of serine dipeptide lipids of Bacteroidetes bacteria in human arteries: relationship to atherosclerosis"

- "The immune system in atherosclerosis" https://www.nature.com/articles/ni.2001

- "Is atherosclerosis an autoimmune disease?" https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-...

- "Atherosclerosis and the role of immune cells" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391004/

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Re:Total cholesterol and all-cause mortality – a study among... by Gibbon1 on Sunday June 09, 2019 @08:10PM (#20142767)

> TC is probably not a great measure on an individual basis, but sort of interesting population-wide.

I keep getting the impression that using TC as a guide the ratio of number needed to treat vs morbidity reduced is kinda dismal.

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Re:Total cholesterol and all-cause mortality – a study among... by YeGoblynQueenne on Sunday June 09, 2019 @12:31PM (#20140154)

Thank you for the links. My understanding is also that TC is not a very good predictor of cardiovascular health, but I'm not any kind of expert on the matter, or even close.

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