If they release the leash and let people book "extra" tickets when they miss a flight, next thing you know people will be taking their S.O. along on conferences using "rescheduled" tickets or having the company pay for vacation tickets and so on. An interesting unofficial benefit, not necessarily a bad idea if it can be controlled. However people always push the boundaries and next thing you know...
So it saves money in the long run to have one employee traveling equals precisely one (admittedly expensive) ticket. They can put their oversight labor into preventing more elaborate forms of control fraud such as using sales meeting budget for dating purposes or padding wedding receptions into corporate meeting budgets or all the nonsense that happens with "company" cars.
Also the labor savings of phoning it in by taking a week to approve tickets means it could be very expensive indeed to have a protocol that permits same day travel if you need to reschedule, all those tickets being approved at considerable labor expense same day just in case you need one once a year. Or paying you for a week to sit there waiting for tickets to arrive, etc.
A side dish is small companies have control fraud oversight as a small rounding error, but when you start thinking about an entire department to organize travel, now you need oversight of an entire department, leading to strange inefficiencies.
The other side is that a large company often gets large contracts. If you sell a software 10 million times it doesn't really matter if you spent 100x as much on it as a small company would. The small company with 10000 customers still is having 10x the revenue per work done.
Could you make more profit? Sure, but lacking market pressure you're rarely concerned with efficiency.
I just noticed my company always books flexible airline tickets. They cost about 2x as much as non flexible ones. I've never missed a flight and most of my colleagues haven't either. It makes sense if you're a busy manager that often doesn't fly. But for most engineers the flexibility costs more than what it's used for.