Not really. I worked in a Winn-Dixie in high school during the pre-barcode era. The products were marked with a price gun that applied a sticker. But of course, sometimes the can of corn didn't get a sticker or the sticker fell off, so you learned what the price was to avoid holding up the line while you called for a price check.

Side-effect: I would have cleaned up on "The Price is Right" if they'd let a kid on the show, since I knew what everything cost.