This used to drive me freaking bonkers -- I was installing caching plugins, offloading static resources to other domains, tweaking the number of worker processes, etc etc. Nothing worked, and my blog regularly crashed almost every time it hit an audience larger than HN's. Turned off KeepAlive, bam, no problems since.
Perhaps I should write a blog post about this.
ab with 500 concurrent, keepalives: Requests per second: 14403.98 [#/sec] (mean)
Keepalives allow the browser to maintain a socket between the browser and server and request multiple objects. So, rather than having to do a connect/teardown for each object, you remove that overhead. Some versions of Apache in conjunction with php and mysql_pconnect had issues in the past that might explain the OP's issues with keepalives, but, it has piqued my curiosity. In general, keepalives should reduce communication handling and allow more throughput.
The real error was posting it there in the first place and not directly on the Jamendo blog... Never again! :)