Paradoxically, they are way more usable. They are the only phones (on some Sony too, but with several caveats) where it's easy to compile and install your own AOSP.
Lots of security focused efforts aim at Pixels for this reason. See CopperheadOS and its successor [1].
With the advent of device independent ROMs (thanks to Treble) it will be a bit easier to run generic ROMs on any phone. But there are still many glitches [2].
[2] https://github.com/phhusson/treble_experimentations/wiki
It works quite well! Having not used 'normal' Android (anything that's not Lineage/Cyanogen) for years, I attempted to start out using this phone with the stock Google Android build. I disabled all the bundled crapware (Play Music, Play Movies, Play Games, YouTube) and they all kept re-enabling themselves. If you're looking for a device that will help you avoid Google at least a little bit, look at this page first. https://wiki.lineageos.org/devices/
https://www.apkmirror.com/apk/google-inc/camera/
The camera quality and features are the same as in the stock ROM.
Google Camera is proprietary, but you can disable its internet access through the app settings (in LineageOS) or a firewall like AFWall+:
https://github.com/ukanth/afwall/
If you're using another camera app, then you'll lose Google Camera's optimized features. This may still be worth it if you prefer to use FOSS software.
If you order it from Google, it's stock Android, so it's the most un-locked-down OEM OS you can get. This may not be the case if you buy it from a carrier.
This feels like a very dumb question, but are the current Google phones any less usable than other Androids for people who are keen to avoid going all in on Google services?
I have an Android phone and use the Play store with it, but I don't use Gmail, I don't store my contacts in my Google account, I have Assistant disabled, and I generally use an OSM maps app rather than Google Maps. I appreciate that this makes no meaningful difference to my online footprint, but it pleases me. Is there anything about the Pixel hardware or Android builds that would not sit well with this?