Spider-Man has been rebooted twice in live-action movies since the Raimi version. The last and current incarnation, starring Tom Holland, debuted in Spider-Man: Homecoming, which is getting a sequel this year (Spider-Man: Far From Home). The other reboot, starring Andrew Garfield in two movies, was eminently forgettable.

"Spider-Man into the Spider-Verse" is an alternate-reality version (where SM is a black/latino teenager) in animated form. Somewhat surprisingly, it's also qualitatively better than any live-action version to date. It will probably get a sequel, again in animated form, in the next few years.

There's technically two more...from a certain point of view. Spider-Man: Homecoming, the latest live action Spider-Man film and there was a brilliantly done (both story and the use of CGI and visual effects to enhance and supplement the story) animated movie "Into the Spider-Verse". Coming soon is the sequel to said live action movie.

They're not connected to each other, beyond the two live action movies, and none of the above are connected to the Raimi Spider-Man movies--if that helps your frame of reference.