I've had a similar experience as the GP, and I find it awful that autoplay videos will follow you around the page, pop-up modals will interrupt you in the middle of reading something, and ads will take up 40% or more of the page, loading between paragraphs while reading. It's hugely distracting to me.

We could make the same argument: you've spend years without adblock, and they have worn you down to the point where you accept active mental blocking of highly distracting ads. And even then you say sometimes it's bad enough for you to leave the site.