This. We evolved in an environment with plenty of particulate matter. It's the exotic stuff that has no analog from the time when we evolved that causes problems.

As opposed to acrylic?

Without knowing for sure, I imagine acrylic to be inert and most like any other dust on the time scale it takes for our bodies to expel it. But I could be wrong. Certainly, there are modern dangerous materials which do affect us, such as asbestos and heavy metals.