>Then a UK study comes out (PACE) saying patients should engage in activity to help themselves. This only makes the patients worse and eventually so bad that the study was pulled.

For those unaware, the PACE study is a famous for exposing the worst aspects of modern medicine. It twisted statistics and definitions to the point that patients whose conditioned worsened were declared cured, they fabricated death threats against themselves to discredit their critics, and are generally notable for the harm they inflicted upon patients and future research into CFS.