It could also be measuring the result of extreme inactivity. I am bedridden, and I have no doubt that lying in bed for years has had a profound effect on my physiology independently of my ME/CFS.

The acid test will be when we compare ME/CFS patients to matched MS patients. However, as Ron Davis has stated, it might also be the case that MS patients have ME/CFS, as ME/CFS is highly heterogenous and may be arrived at from multiple directions.

There are lots of details that need to be ironed out. Nevertheless, this is exciting news.