Most are clinically silent. The ones that land you in an emergency room are dangerous.
A few years back, I was blinded in one eye by a retinal vein occlusion (basically a stroke in the retina). They're actually pretty common, affecting 5-10% of the population, but unless it crosses your macula, you'll probably never know it happened.
Eye issues terrify me and I'm not sure mental state could handle a retinal stroke. That sounds truly horrible.
Hooray for modern medicine! It saved my eye. When the occlusion first happened, my vision went from 20/20 to 20/500 in moments.
But if it gets the point of even minor persistent chest pain or one is aware that something is not right, it's time for the emergency room.
Chest pain is not to be trifled with. One clot may be followed by others which might be serious or fatal in a very short time.
PE is common enough among people that sit for a living (most of HN), that I think it's important for folks to be aware of them and that they're dangerous.