The new DIMMs Intel is putting out have a RAM cache in front of the optane memory that will absorb all the churn plus a wear leveling algorithm on the writeback side. It has big enough capacitors to put all its data away in the event of power loss.
https://www.storagereview.com/intel_optane_dc_persistent_mem...
All of which looks to solve the wear problem even if it means higher price and latency.
SemiAccurate's singing a different tune this year, now that Intel has stated that the Optane DC Persistent Memory modules are warrantied for 5 years regardless of workload. Intel's gotten write endurance up to sufficient levels for use as main memory, though if you use those DIMMs as memory rather than storage, then your DRAM will be used as a cache.
Take a look at how cagey Intel is acting about Optane: https://www.semiaccurate.com/2018/05/31/intel-dodges-every-q...
This is the same behaviour as with Intel's LTE chips, where promised features keep slipping (much to Apple's dismay).