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Re:The Rise Of The Gentleman Hacker by bioh42_2 on Friday December 03, 2010 @04:09PM (#1967442)
I don't need convicing that it is easy to inovate outside of big pharma. Altough bioinformatics startups do require quite a bit more cash then pure software startups.

However, the biggest part of capturing value is the regulatory burden.

In other words, lets say you have a great way to discover biomarkers. Even more so, you go ahead and DO discover a pile of biomarkers with great potential.

Then you attemp to sell those biomarkers to big pharma, and that is when you find out:

Even with all their beurocracy and horrible return on R&D investments, big pharma is sitting on a huge pile of biomarkers.

Pushing any one tratment through the pipeline costs a metric tonne of cash and takes 10 year before you even know if it's worth to keep going.

That is why there's a huge backlog of potential drugs, biomarkers, treatments, etc.

Thus merely finding new things with potential is only slighlty better then nothing.

Re:The Rise Of The Gentleman Hacker by blakeweb on Friday December 03, 2010 @06:13PM (#1967814)
Agreed. You've got to address the real problems, or you won't get anywhere.