Anybody who has worked at a fortune 500 tech company knows how much security (physical, IP, etc.) tends to be a joke. To the degree that such security works its often due to the lack of serious threats and the ubiquity of individual discretion. As more institutions with serious resources and an anti-secrecy agenda come into existence and grow in stature and capability this comfy situation will likely devolve. In the near term that might lead to a lot of very unhealthy reactionary responses. More NDAs, more security, police state tactics being deployed throughout the tech industry (as an example). We can look to the responses of the RIAA/MPAA to modern communication technology as a yard stick for the way the typical corporate mind might react to the onslaught of "openness" that wikileaks and its ilk will cause.

Similarly, how will government respond? We see the sort of ridiculousness that we already have to put up with (TSA pat-downs, porno-scanners, liquid limitations, other security theater), what new travails will the public have to put up with?