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Re:Herpes Virus Reactivation in Astronauts During Spaceflight by ncmncm on Monday March 18, 2019 @03:46PM (#19424474)
The article doesn't mention, among possible stressors, that spacecraft are always operated at reduced air pressure and high oxygen fraction, and low humidity.

The problem is, nobody knows which factors are actually responsible for downregulating immune system activity, because every astronaut gets all of them.

A few ought to be variable. Sleep deprivation ought to be entirely avoidable, but NASA cannot quite manage not scheduling more to do in a day than there is day.

Re:Herpes Virus Reactivation in Astronauts During Spaceflight by sitharus on Tuesday March 19, 2019 @12:20AM (#19428054)
ISS, Soyuz and soon the crewed Dragon 2 all operate at sea-level air pressure with standard o2 partial pressure. Apollo was the last high oxygen environment.
Re:Herpes Virus Reactivation in Astronauts During Spaceflight by benj111 on Monday March 18, 2019 @04:53PM (#19425166)
"The problem is, nobody knows which factors are actually responsible for downregulating immune system activity, because every astronaut gets all of them." They could check? Might be a good idea to know before they send Astronauts to Mars or something?

None of your examples are space dependent, and compared to SLS, slightly cheaper.

Re:Herpes Virus Reactivation in Astronauts During Spaceflight by jamesmontalvo3 on Monday March 18, 2019 @11:55PM (#19427959)
ISS is at 1 atmosphere, except in the airlock when preparating for a spacewalk.