I'd also like to point you to Clay Christensen's theory of disruptive innovation. One of the parts is that well run companies while doing everything optimally will lead themselves to destruction because they will laugh and scoff at the idea of being involved at the lower-end market brought on by new technologies.
Then theres also the internal resistance within the company. Imagine trying to staff up a small team to checkout a possible new technology to do X. No rational manager will want to take that opportunity as it is clearly a fool's errand. They'd rather stay and be the manager for the profit generating center, rather than go pursue some foolish idea that clearly will never go anywhere.
So what you end up with is many, many reasons why the best companies miss the ball on where the market was moving to in an obvious (in hindsight) way.
And for publicly-owned companies, resisting is rarely feasible because a majority of shareholders will find it to be a risky proposition (and a majority may have invested in hopes of a takeover, anyway.)
It is rare for a startup to grow large enough to challenge an entrenched incumbent in a large market without taking on a majority of investors who are not necessarily committed to fighting for independence.
[1] https://www.recode.net/2017/3/29/15112314/amazon-shutting-do...
One way to do this would be to require public APIs, so that competitors can make rival designs/experiences.
For example, if Amazon uses its monopoly to only show its own products in the first page of search results, even when they cost more or have worse reviews, then a competitor could build an interface that does better.
Also, I don’t think there is much value add if companies are just reverse engineering the incumbent. If Google allows another company to get its search results easily to copy search, did the world improve?
Google’s moat was partially disrupted by Facebook, a closed network, and mobile/mobile apps.
Your last example has occurred for a number of years with shelf space at grocery stores and pharmacies. The CVS branded Advil is cheaper, and CPG companies can pay to get the best shelf space.
My understanding of "breaking up" is the artificial creation of competition when organic competition cannot come to fruition on its own.