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Re:Ask HN: Tricks to Avoid Eye Problems? by damnruskie on Wednesday March 13, 2019 @10:25PM (#19386035)
havnt tested on a mac but I use zathura on linux and its reverse colors (cntrl+r) is a lifesaver for me.

this seems promising: https://github.com/zegervdv/homebrew-zathura

Re:Ask HN: Tricks to Avoid Eye Problems? by orn688 on Wednesday March 13, 2019 @11:43PM (#19386371)
Wow, that looks perfect, thanks!