Have you tried the new JupyterLab interface yet? It's pretty straight forward to segregate your content into separate notebooks in that setting since you have quick access to a filesystem view. That said, I also have a wiki with 10+ years of my medical notes in it. I love the wiki, but work keeps blocking my domain (I have lots of images from med school that I'm sure have a copyright on them, so I can't just make the wiki public access, therefore the little ladies in tennis shoes at BrightCloud mark it as "personal storage".