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Re:Square Inc. Co-Founder Tristan O’Tierney Dies at 35 by sizzle on Sunday March 03, 2019 @03:38AM (#19293431)
This is super interesting, as someone with that mutation that gets extra sedated/euphoria from drinking and is predisposed to alcoholism, from a family tree full of alcoholics.

What do you think the lsd did to dampen the effects on opiate receptor to release endorphins? I have experimented with naltrexone and it works well to block my opiate receptors when drinking. It just scares me that I'm blocking all euphoria and how I'm messing with neuroplasticity and encoding long term memories... Thoughts?

Re:Square Inc. Co-Founder Tristan O’Tierney Dies at 35 by knownhoot on Sunday March 03, 2019 @10:13AM (#19294782)
similar situation -- have had a lot of success with nal. but now curious about the neuroplasticity you mention. curious if you have any further reading on this. I'm reading Pollan's new book "How to Change your Mind" and it makes me very interested in exploring LSD more for similar addiction purposes.