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Re:Four new DNA letters double life’s alphabet by physicsyogi on Friday February 22, 2019 @11:44AM (#19226734)
Someone could also replace the carbon with silicon.
Re:Four new DNA letters double life’s alphabet by anticensor on Friday February 22, 2019 @02:49PM (#19228502)
Silicon/Bismuth biochemistry is way more limited than Carbon/Hydrogen Oxide biochemistry in terms of temperature range and stable compounds. Silicon/Hydrogen Sulfide biochemistry does not work at all because hydrogen sulfide does not have the point of least volume.

biochemistries listed here are denoted as bonding atom/solvent pairs.