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Re:Esketamine Drug For Depression Treatment Nears FDA Approval by rincebrain on Wednesday February 13, 2019 @08:18AM (#19152781)
People seem to still be arguing about that - [1] and [2] argue that they're directly correlated in ketamine treatment, and I can't begin to guess what research on {ar,es}ketamine and metabolite efficacy is going to produce when one of these becomes readily available.

[1] - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065787/

[2] - https://www.ncbi.nlm.nih.gov/pubmed/29501990

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