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Re:Bootstrap 5 will remove jQuery as a dependency by frosted-flakes on Wednesday February 13, 2019 @12:25AM (#19150676)
Is CSS Modules considered to be "CSS-in-JS"? It does require JavaScript to import the class names, but the stylesheet itself is static. I personally find it to be a great solution to the scoping problem, and combined with Sass it's very flexible. Even theming is a cinch with a single shared Sass file with theming variables, or CSS custom properties.

Every CSS-in-JS library I've tried makes everything way too cumbersome with no real upside. I especially hate how they all spread my style declarations all over the place.

Re:Bootstrap 5 will remove jQuery as a dependency by mercer on Wednesday February 13, 2019 @05:30PM (#19157775)
I can't answer your question, but after a lot of experimenting and reading I ended up with styled-components as my preferred solution if I were to go the SPA way.

It allows you to write your CSS inside the backtick js strings (template literals?) and then inserts/removes the relevant CSS as components are loaded/unloaded.

Personally I've gone in an entirely different direction (server-side everything, and simply diffing the HTML on the client when necessary), but if I were to build a proper front-end app, I'd probably go for styled-components.

The main downside is that the stuff needed to parse the css-in-js-string is yet another thing that increases payload size, but for an app it's not too bad.