Your examples lean towards the "managed by a trained physician", which would make sense. Treat depression, reverse neurodegenerative disorders, sure, a Dr can oversee that and treat that.

I was referring specifically to the DIY crowd, which this articles discusses. Things a Dr would say "no, I'm not going to help you with that". Or as the quote discusses, things a drunk person would say "I think this is a good idea".

Definitely these are not extreme joy riding, but I don't think an ethical doctor would help with highly above normal neuron growth, wakefulness, testosterone, or get involved with experiments starting from near normal levels in a patient. They might have some serious problems with a medical board.

It's a bizarre case that doctors will help normal people (journalists) experiment with some levels of sport doping, but it comes from knowing a little about the experimental professional sport dopers (where doctors try to stay anonymous.)

To give a different example, what about an anorexic that wants their genes to ensure their desired body image, i.e. 0 retention of normal fat? (Personally, I would be more concerned about bulk experiments in the beauty salons than the tattoo parlours.)

If there was one to put my body on a 24 hour sleep/wake schedule I'd be in line.