The nice thing about how the Matrix Profile is built is that you can slice up different regions of time to focus on your use case. To build the MP you start with an NxN matrix that lists the distance between every point (or technically N-m+1 x N-m+1), then find the overall closest distance for each point. However, we've found that first "updating" the NxN matrix allows you to do analyses like your two anomaly example.

In that case, you'd create a parameter "w" that specifies the boundary between when two matching points are a pattern, or if enough time has elapsed so that they should be considered two anomalies. In the NxN matrix, for the ith row you'd then set every value outside the i+w/i-w boundary to infinity. In that way, the resulting Matrix Profile would account for your situation.

Due to the algorithm's speed we do often sweep over multiple values, but try to use domain knowledge where we can. And for alerting, we sometimes have labeled data that we can calibrate the threshold to, but often times that's a matter of customer trial and error.