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Re:By growing cells in unrealistic liquids, scientists may h... by pvaldes on Thursday January 03, 2019 @02:12PM (#18818182)
As an aquarist I find this hilarious. For $399 you could hire an expert in fish pathology to check that the fishes are free from diseases and spend the other dollar into buying the real fishes, and put it in a quarantine tank then.

> the facility in Europe had suffered a fire that required them to stop production for 4-6 months.

This sounds very strange, unless you want to artificially create a scarcity in the supply of an animal that anybody can breed by thousands in their living room. You don't need almost any space to breed this fishes, and aquariums can be moved right?. 6 months seem too much.

I wonder why nobody has tried with another of the 100000 species of fish with transparent embryos and bypass this money-grabbing structure.

Re:By growing cells in unrealistic liquids, scientists may h... by Balgair on Friday January 04, 2019 @03:40PM (#18827401)
The issue is the genetic 'cleanliness' of the animals. Some zebrafish will only glow red when you feed them special stuff, some glow green, some only glow green in certain parts of their yolks/chorion. Sometimes this only happens with every other generation of females.

It's very complicated and quite 'messy' when it comes to the phylogeny/genetic trees. Most of the time, researchers only need those 20 fish or so once every few years, if that. Sometimes they need to interbreed these different fish to glow green and red. There are literally tens of thousands of types of fish that have to be kept. As an example: Jackson Labs has mice ready to order to the specific genotype that you want and it gets very specific [0]; zebrafish aren't quite at that level yet, but are getting there.

But the effort is worth it. Zebrafish are a great animal for studying neuro development and many other things. Many of the proposed treatments for ALS, Alzheimer's, Parkinson's, etc. got their start in zebrafish and in studying how those little vertebrates function. The effort will save countless human lives.

[0]https://www.jax.org/strain/008199

Re:By growing cells in unrealistic liquids, scientists may h... by jonlucc on Friday January 04, 2019 @03:32PM (#18827351)
Sure, you can hire the fish pathology expert (or send samples out to a lab), but our facility requires us to have "clean" fish coming in, so we can't do the exercise of breeding, treating, and certifying fish in our own facility. The same is true of mice and rats. We have many pathologists on staff who could certify such a thing, but it would require setting up a "dirty" facility completely separate from the "clean" ones (complete with a separate animal care staff to change cages and such). Overall, the price is justifiable to avoid the trouble.

You wouldn't even need a different specie to bypass the money-grabbing, you only need a new facility, your own certified processes, and some clout in the industry (read citations). Hell, you could start with the fish from the expensive vendor and sell the offspring (I think, unless there's a licensing agreement involved).