the receptors responsible for escorting insulin across the blood-brain barrier can become resistant to insulin, restricting the amount of insulin allowed into the brain. While most brain cells don’t require insulin in order to absorb glucose, they do require insulin in order to process glucose. [..] Despite swimming in a sea of glucose, brain cells in people with insulin resistance literally begin starving to death. [..] Which brain cells go first? The hippocampus is the brain's memory center. Hippocampal cells require so much energy to do their important work that they often need extra boosts of glucose. While insulin is not required to let a normal amount of glucose into the hippocampus, these special glucose surges do require insulin, making the hippocampus particularly sensitive to insulin deficits. This explains why declining memory is one of the earliest signs of Alzheimer’s, despite the fact that Alzheimer’s Disease eventually destroys the whole brain.

researchers have discovered that Alzheimer’s Disease is preceded by DECADES of gradually worsening glucose hypometabolism.

2012 study showed that a low-carbohydrate high-fat diet improved memory in people with “Mild Cognitive Impairment” (Pre-Alzheimer’s Disease) in only six weeks.

https://coconutketones.com/ - Dr Mary Newport's work on coconut oil and low carb diet with her husband with early onset alzheimers and dementia, intended to provide an alternative ketone source of fuel for the brain instead of glucose.

Grain and sugar elimination: that’s huge, because it’s anti-inflammatory. A big driver of cognitive decline and dementia is inflammation. By going grain-free sugar-free we drop inflammation dramatically. If you were to track inflammatory measures like C-reactive protein or interleukin-6 or tumor necrosis factor (TNFα) or other measures, you would see them drop precipitously, as inflammation recedes, and risk for Alzheimer’s with it. - https://www.wheatbellyblog.com/2017/11/preventing-cognitive-...